AMML - Slide 3
Images from a patient with an acute leukemia with monocytic characteristics (
180⋅109/L
Leukocytes). The anomalous cells have dark blue cytoplasm with a large nucleus, immature chromatin and nucleoli. Some cells (and nuclei), contain vacuoles.
Blasts
Promyelocytes
Myelocytes
Metamyelocytes
Bands
Segments
Eosinophils
Lymphocytes
Monocytes
Erythroblasts
Smudged
XN Scatterplots
Lymphocytes
Monocytes
Neutrophils & Basophils
Eosinophils
Leukocytes
Basophils
NRBCs
Debris
Erythrocytes
Reticulocytes
RBC fragments
Platelets
immature platelets
Immunophenotype
CD34-
CD117-
HLA-DR-
CD33+
CD64+
CD11c+
CD14+
The majority of the aberrant population is positive for the monocytic markers CD64, CD11c and CD14. APL cells usually do not express these but are CD117+.
SSC
CD45
SSC
HLA-DR
CD34
CD117
CD64
CD11c
CD14
CD33
Peripheral blood
Blasts
Smudged
Neutrophils
