B-ALL - Slide 4
An acute lymphatic leukemia combined with prominent presence of aberrant erythroblasts, some aberrant monocytes, hypogranular neutrophils and macrothrombocytes. Several months prior to the presence of blasts, an MDS or CMML was considered because of the dysplasia and monocytosis.
Progression from an MDS or CMML to an AML is not uncommon, but transformation to a lymphatic form of acute leukemia is fairly rare. The exact cause is not known. The total leukocyte count was
15⋅109/L
. The number of erythroblasts 4.7⋅109/L
.
Blasts
Promyelocytes
Myelocytes
Metamyelocytes
Bands
Segments
Lymphocytes
Monocytes
Erythroblasts
XN Scatterplots
Lymphocytes
Monocytes
Neutrophils & Basophils
Eosinophils
Leukocytes
Basophils
NRBCs
Debris
Erythrocytes
Reticulocytes
RBC fragments
Platelets
immature platelets
Immunophenotype
TdT+
HLA-DR+
CD19+
CD20±
CyCD79a+
CD10+
SSC
CD19
TdT
CD22
HLA-DR
CD22
CD20
CD10
cyCD79a
MPO
Peripheral blood
Blasts
Monocytes
Neutrophils
Macrothrombocytes
Erythroblasts
Erythroblasts II
In the days following the initial diagnosis, erythroblasts remained prominent.
