CellMasters 2025
CellWiki
Hematology
Unclassified - Slide 1
Except for a single blast, a monoclonal population is not immediately apparent in this preparation (all lymphocytes are shown). What does stand out tremendously is the extreme number of ruptured cells (6x more than what is currently shown). Due to improper production, malignant cells are more fragile than usual and can easily break down when swabbing the blood for a specimen. Immunophenotyping indeed finds a 30% monoclonal B-cell population (90% Lamba+).
Blasts
Neutrophils
Lymphocytes
Smudged
Monocytes
Immunophenotype
CD19+
CD20+
CD5-
CD10-
CD23-
CD22+
FMC7+
Kappa-
Lambda++
Peripheral blood
Blasts
Lymphocytes
Smudged
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