CellMasters 2025
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Hematology
AMML - Slide 8
Usually, the nucleus of a monoblast is fairly round and centrally located, but in this acute monocytic leukemia this is not the case. These monoblasts exhibit an eccentric and oval shaped nucleus. The morphology is reminiscent of promyelocytes without granulation. Immunophenotyping, however, shows monocytic maturation.
Blasts
Monocytes
Neutrophils
Lymphocytes
XN Scatterplots
Immunophenotype
CD34-
CD117±
HLA-DR++
CD13-
CD33+
CD4+
CD14-
CD64+
CD11c+
CD11b+
Peripheral blood
Bone marrow
Blasts
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