T-PLL - Slide 1
Prolymphocytic Leukaemias (PLL) are rare forms of leukaemia which involve the proliferation of immature T-lymphocytes. In this case, the proliferation manifested itself as a leukocytosis of
400⋅109/L
with many smudged cells. The morphology is classic for prolymphocytes; a relatively large cell with a very prominent nucleolus.
Neutrophils
Lymphocytes
Monocytes
Immunophenotype
CD3+
CD2+
CD5+
CD7+
CD4+
CD8-
TCRαβ+
TCR-Vbeta3+
CD38±
HLA-DR-
TdT-
CD34-
Peripheral blood
Prolymphocytes
