AMML - Slide 5
An acute myeloid leukemia with predominantly blasts, promonocytes and monocytes. The leukocyte count was
15⋅109/L
. Officially, promonocytes are not blasts, but are counted as such for the diagnosis of AML ("blast equivalents").
Blasts
Promonocytes
Monocytes
Neutrophils
Lymphocytes
Erythroblasts
XN Scatterplots
Lymphocytes
Monocytes
Neutrophils & Basophils
Eosinophils
Leukocytes
Basophils
NRBCs
Debris
Erythrocytes
Reticulocytes
RBC fragments
Platelets
immature platelets
Immunophenotype
CD34-
CD117+
CD13+
CD33+
HLA-DR+
CD11c±
CD14-
CD64±
MPO±
The blastoid population in the bone marrow shows progression into a more mature monocytic population through the expression of CD11c, CD64 and MPO (black arrows). The expression of CD7 is abnormal.
Peripheral blood
Bone marrow
Promonocytes
Blasts
