The White cell Nucleated Red blood cell (WNR) channel is used for the determination of erythroblasts (NRBCs), leukocytes (WBCs) and basophilic granulocytes. Erythrocytes and platelets are lysed, while the remaining cells are permeabilized, after which intracellular nucleic acids are fluorescently stained. The staining intensity is represented as SFL. Cells are then classified based on cell size (FSC) and SFL signal.

The WNR channel is more acidic and hypotonic than the WDF channel, making it specifically suited for this strong lysis of erythrocytes and platelets. Any elements that do not lyse (such as platelet aggregates) can interfere with the counts.

Although this channel is not used for further differentiation, on the eye the granulocyte , lymphocyte and monocyte populations can also be seen.